Christina Applegate on life with multiple sclerosis: ‘I won’t lie and say any of this is a blessing’

When the Emmy-winning comedy star was diagnosed, her body started giving up on her. She writes about losing control, gaining weight – and refusing to be a ‘good girl’In 2021 I was diagnosed with multiple sclerosis. MS attacks your nervous system and slows down your functions – your respiratory system, your organs, everything. The disease eats away at all the things we take for granted. Some of us with MS have a raft of pain; some don’t. I have a lot of it. When I wake up, I often can’t get my arm to move far enough to grab the cup of water by my bed or my phone from its charger. I have infusions every six months to slow the disease’s progress, but those infusions kill all my B cells [a type of white blood cell that makes antibodies], making me prone to infection. My stomach frequently slows to a halt, leaving me to rush to the emergency room in agony. Most days, simply walking across the room feels like scaling a mountain.One of the worst side-effects of the illness is the exhaustion. ...


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