32 m. ago ‘It’s not ethical and it’s not medical’: how UK rehab clinics are cashing in on NAD+

They are beloved by A-listers and surging in popularity. But claims that NAD+ infusions are a fix for addiction are unproven, risky – and possibly illegal, an Observer investigation revealsIt is billed as a “miracle” treatment that can reverse ageing and regenerate brain cells. And getting hooked up to IV drips containing NAD+ has surged in popularity, with record Google searches and celebrity fans such as Kendall Jenner and Joe Rogan.Now NAD+ is being touted in the UK as a treatment for substance ­misuse. Infusions of NAD+, which is derived from vitamin B3, are being sold across the country as a ­“clinically proven” and “effective” way to quit drinking or get off drugs. Continue reading...

Science

2 h. ago Country pub of the week: The Crown in Mundford is an old courthouse serving Murphy's

A pleasing Norfolk pub serving ham, egg and chips and lots of gin

Events

2 h. ago The Australian Dream? There’s a dark side to moving down under

Nearly 50,000 people moved from the UK to Australia on a working holiday visa in 2024. But while many of these sun-seekers enjoy a new life or a long holiday, others are unsettled by the country’s politics and pop culture. Kyle MacNeill speaks to the young Brits left disillusioned

Politics

2 h. ago I saw the devastation of homes burned and a school destroyed in Gaza

When the news of the October 7 attacks broke, I could never have imagined the devastating consequences of that Hamas attack and the subsequent war, and the horror that continues to unfold in the region.

Events

3 h. ago AP PHOTOS: Ukrainian soldiers who returned to the battlefield after amputation

Many Ukrainian brigades have at least one, often several, amputee soldiers still on active duty, who chose to return to combat driven by the sense of responsibility amid the grim outlook for their country.

Events

3 h. ago Wounded, recovered and back to war. Ukrainian soldiers are returning to battle after amputation

Ukrainian soldiers who lost limbs in the three-year war against Russia are returning to the battlefield out of a sense of duty amid the grim outlook for their country

Events

3 h. ago Ohio bathroom law targeting transgender students has brought internal strife to some campuses

An Ohio law designating school bathrooms for use by people based on their sex at birth kicks in soon

Society

3 h. ago German voters head to polls facing world of change as far right waits in the wings

Europe holds its breath as world’s third largest economic power and most populous EU country faces crossroadsGerman voters go to the polls today but it is a different world from when the campaign began only a few weeks ago.Nearly 60 million ­people are choosing a government that will have to grapple with the breakdown of the transatlantic alliance under Donald Trump and new threats to European security just as the country’s vaunted economic model is hitting the skids. Continue reading...

Politics

3 h. ago Country with the world's weirdest pizza shocked Italians say 'shouldn't be allowed'

Sweden may be known for IKEA, ABBA, herring, tall blond men and Premier League strikers who play for Newcastle, but it is also home to a culture of unusual pizza toppings

Events

4 h. ago Council chiefs making fire and rehire threats should be sacked, union suggests

GMB Scotland secretary Louise Gilmour has spoken out after two local authorities allegedly made threat in pay negotiations.

Events

4 h. ago Schoolgirl, 11, brutally murdered by man who lived in back garden before hiding body

Audrii Cunningham was a happy girl who enjoyed reading and art, but little did she know there was a monster on her doorstep

Events

6 h. ago Pizza, cereal, crisps and yogurts among 16 food and drink items facing supermarket ban

The new rules are set to be introduced in medium to large food shops and supermarkets

Politics

6 h. ago SIR CLIVE WOODWARD: Why my glass is half full despite England's lucky victory and the encounter with Scotland fans that made win sweeter

SIR CLIVE WOODWARD: England's last two Six Nations games haven't been good for the heart rate of the country's rugby supporters.

Events

7 h. ago Coming to a cinema near you: six British kids playing Roblox...

The stars, six British junior schoolchildren, were recruited via Facebook and a casting agency to play each other on the Roblox video game platform for the film to launch on April 19.

Politics

7 h. ago The area of Wales that has rejected getting rid of 20mph on 143 roads, and people are not happy

The default 20mph speed limit was piloted in the county and now the council has rejected every application to change routes back to 30mph

Politics

7 h. ago Hunter Schafer on why she spoke out about being issued a male passport

Hunter Schafer says “it’s important to just keep track of where things are in our country,” a day after the “Euphoria” star posted a video in which she revealed her new passport had been issued with a male gender marker

Politics

7 h. ago Party of one: Donald Trump’s 75 minutes at CPAC talking about himself

Contemptuous and sure of himself, the US president boasted of his victories and taunted his enemiesGod save the king. Drunk on power, Donald Trump spent Saturday afternoon before adoring fans, boasting of his victories, taunting his enemies and casting himself as America’s absolute monarch, supreme leader and divine emperor rolled into one.Trump’s appearance at the Conservative Political Action Conference (CPAC) at the National Harbor in Maryland began with country singer Lee Greenwood’s “God Bless the USA and raucous cheers in a crowded ballroom that included January 6 insurrectionists. Continue reading...

Politics

9 h. ago Doing one thing for '31 to 45 minutes' before bed may worsen your sleep, experts warn

The study saw 435 adults asked seven key questions about their bedtime usage of smartphones and snoozing habits

Events

9 h. ago Cycle lane snowflakes: Council duo cancel meeting with opponents of 'barely used' 50

Councillors Andy Hadley and Richard Herrett were due to face a public meeting in Dorset to discuss the £120 million spent on 50 miles of cycle lanes.

Politics

10 h. ago Artists who represented Australia at Venice Biennale call for Khaled Sabsabi to be reinstated

Open letter from some of the country’s most distinguished artists ‘strongly protests’ at the removal of Sabsabi and curator Michael DagostinoGet our breaking news email, free app or daily news podcastLiving artists who have represented Australia at the Venice Biennale over the past five decades – and the estates of a number of now deceased artists who have done the same – have signed an open letter to the board and chief executive of Creative Australia to reinstate sacked artist Khaled Sabsabi and his curator Michael Dagostino.Some of Australia’s most distinguished living artists, including Imants Tillers, Mike Parr, Susan Norrie, Fiona Hall, Judy Watson, Patricia Piccinini and Tracey Moffat have signed the petition, as has the estate of Howard Arkley who represented Australia in Venice more than a quarter of a century ago.Sign up for Guardian Australia’s breaking news email Continue reading...

Politics