29 h. ago New gonorrhoea treatment hailed as breakthrough in fight against drug resistance

Researchers say gepotidacin could be delivered via a pill and help combat strains resistant to standard treatmentScientists have hailed a new antibiotic treatment for gonorrhoea, the first in three decades, which they said could help combat the global rise of drug-resistant infections.The sexually transmitted infection can result in serious complications if it is not treated promptly, especially for women, for whom it can lead to increased risks of ectopic pregnancy and infertility. Continue reading...

Economics

61 h. ago What I’ve learned after 40 years as the Observer’s science editor

Almost as amazing as the knowledge we have gained in the past four decades is the fact that some people continue to deny the damage we are doing to our worldEarlier this year I received an email from a reader asking background questions about an article I had written more than four decades ago. Given the time gap, my recollection was hazy. To be honest, it was almost non-existent. So I was intrigued – and then astonished when I read the feature.I had written about the British glaciologist John Mercer, author of a 1978 Nature paper in which he warned that continuing increases in fossil fuel consumption would cause amounts of atmospheric carbon dioxide to soar. Global temperatures could rise by 2C by the mid-21st century, causing major ice loss at the poles and threatening a 5-metre rise in sea levels, he warned. Continue reading...

Politics

3 d. ago Supermarket named the cheapest for essentials during the Easter holidays and it's not Aldi or Lidl

Despite a slight price increase, one supermarket continues to lead the pack this week

Politics

4 d. ago Man eats one of UK's most expensive Easter eggs and is surprised by what's inside

Food reviewer Carmie Sellito tried one of the UK's most expensive Easter eggs - the Venchi Chocolate BacioDiDama egg - priced at £68 from Harrods, London - and he was surprised by what he found inside

Politics

5 d. ago US egg prices break record high for third consecutive month even as inflation drops

The 12-month inflation rate at 2.4%, down from 2.8% in February, was largely fueled by a sharp fall in gas pricesThe price of eggs continues to soar for American consumers, rising by almost 6% in March even as overall inflation fell slightly.Breaking a record high for the third consecutive month, the average cost of a dozen large eggs hit $6.23 in March – more than double the price just 12-months earlier, according to new figures released by the Bureau of Labor Statistics on Thursday. This surpassed the previous record highs of $5.90 a dozen in February, and $4.95 in January. Continue reading...

Economics

5 d. ago Egg prices continue to increase despite bird flu outbreak slowing

U.S. egg prices increased again last month to a new record-high of $6.23 despite a drop in wholesale prices and no egg farms having bird flu outbreaks last month

Science

6 d. ago Trump tariffs threaten global growth and raise risk of ‘severe shocks’, says Bank of England

Levies have heaped pressure on government finances and increased chance of ‘further sharp correction’, report warnsTrump imposes new tariffs on dozens of partnersDramatic sell-off of US government bondsBusiness live – latest updatesDonald Trump’s sweeping tariffs have put global growth at risk, the Bank of England has warned, heaping pressure on government finances and increasing the likelihood of “severe shocks” to the financial system.The Bank’s financial policy committee (FPC) said its global risk environment had deteriorated and “uncertainty had intensified” since its last update in November, with US tariff announcements contributing to a “material increase in risks to global growth” and inflation levels. Continue reading...

Events

7 d. ago US troops in Europe to stay ‘where they are’, says top general – Europe live

Gen Christopher Cavoli says he is planning to keep forces in same locations amid concerns over deployments in Poland and LithuaniaThe US administration is reportedly considering withdrawing up to 10,000 US soldiers from central and eastern Europe, according to a report by US broadcaster NBC News.The unconfirmed plans are understood to be looking at reducing US presence in Poland and Romania, despite what regional leaders see as a growing threat from increasingly aggressive Russia. Continue reading...

Politics

7 d. ago Chinese nationals captured fighting for Russia in Ukraine, says Zelenskyy – Europe live

Ukrainian president says forces captured two Chinese men fighting for Russia in eastern Ukraine and calls for response from BeijingThe US administration is reportedly considering withdrawing up to 10,000 US soldiers from central and eastern Europe, according to a report by US broadcaster NBC News.The unconfirmed plans are understood to be looking at reducing US presence in Poland and Romania, despite what regional leaders see as a growing threat from increasingly aggressive Russia. Continue reading...

Politics

8 d. ago Politicians want to normalise what’s happening in Gaza. Our moral outrage won’t let that happen | Nesrine Malik

The more shocking the carnage becomes, the more people are punished for speaking out. This just makes it clear how much is really at stakeGraphic images. Distressing footage. Blurred-out posts that only clicking a consent button will reveal. For a year and a half now, disclaimers have hung over what the world sees from Gaza. Sometimes, the scenes stop me in my tracks as they are suddenly recalled, like a nightmare forgotten but then vividly remembered. Except without the relief that it was all a dream. Last week, I watched footage that showed what appeared to be the shattered, headless corpse of a baby. I have seen shredded body parts collected in plastic bags. Heard the screams of the dying and the silence of the dead, as cameras capture them piled together, some in entire families. Israel’s assault on Gaza defies inurement. As time goes by, even as the threshold for what is seen as intolerable increases, the graphic and varied forms of killing continue to scale the hurdle of numbn...

Politics

1 week ago Trump team reportedly lays off some staff working on bird flu response even as disease spreads

Democrats are calling for information about how Secretary Robert F. Kennedy, Jr., will address the bird flu. outbreak

Politics

1 week ago Egg prices keep going up. Here’s the average cost for a dozen across the U.S.

Eggs are becoming harder to source across the country as farmers are forced to kill off millions of birds due to an avian flu outbreak

Economics

1 week ago Hong Kong in frame to host Nations Championship finals and Lions matches

Kai Tak Sports Park favourite to stage event post-2028Stadium to host Spurs, Arsenal and Liverpool in JulyHong Kong has emerged as a candidate to stage future Nations Championship finals at its new Kai Tak Sports Park and would be an ideal British & Irish Lions stopover, according to a senior World Rugby executive.The inaugural Nations Championship finals – the biennial playoffs among the world’s leading international sides – is to be held in London in 2026 with Qatar lined up for 2028 but the Hong Kong stadium is an increasingly popular suggestion for subsequent editions. Continue reading...

Sport

2 w. ago About a third of Americans stop buying eggs due to rising costs, study shows

Data says 34% of those in US stopped purchasing breakfast staple and won’t buy again until costs lower to $5 a cartonAs egg prices have reached record highs, about a third of American consumers have stopped buying them in response to the rising costs, a new study suggests.According to research from Clarify Capital, 34% of Americans have stopped purchasing eggs as prices for the breakfast staple are becoming less affordable. On average, these consumers say they won’t begin buying eggs again until costs come down to $5 or less for a carton. Continue reading...

Economics

2 w. ago Full list of areas where 'highly pathogenic' bird flu has been detected across UK

A government map has revealed where strict bird flu prevention measures are in force across the UK

Politics

2 w. ago Wrexham announce record revenue of £26.7m after boost in US popularity

More than half its turnover outside Europe in 2023-24Filming continuing for fourth TV series about the club Wrexham’s increasing popularity in the United States helped the club secure record revenue of £26.7m in their latest accounts, up 155% on the previous year. Wrexham, who are co-owned by Ryan Reynolds and Rob McElhenney, said they generated more than half (52.1%) of that record turnover from outside Europe – primarily North America – for the year ending 30 June 2024.That compared with 24.6% of turnover being generated outside Europe in the previous year’s figures. The club said the spectacular rise highlighted the effect of the “Welcome to Wrexham” documentary series, with the fourth instalment being filmed this season. Continue reading...

Economics

2 w. ago Bird flu is creeping toward human transmission − how do we stop it?

Recent animal outbreaks from a subtype called H5N1 have been especially troubling to scientists

Events

2 w. ago Pensioner, 72, says affording household bills ‘becoming impossible’

Melanie Roberts said she worried about internet and mobile bill increases, as she relied on these services to continue to work and speak to family.

Economics

2 w. ago Trump says he ‘couldn’t care less’ if tariffs make car prices go up

Trump says tariffs on foreign-made cars would would lead to increased sales of US-made carsDonald Trump said on Saturday he did not warn car industry executives against raising prices as tariffs on foreign-made autos come into force, telling NBC News he “couldn’t care less” if they do.The president’s comments came as the White House prepared to impose new tariffs on a range of consumer goods on 2 April, a move that has drawn criticism from international leaders and concerns about potential price increases for consumers.Guardian staff contributed reporting Continue reading...

Politics

2 w. ago Bird flu red flags explained after Government confirmed new UK case

The Government confirmed this week that a single case of bird flu had been identified on a Yorkshire farm

Politics