Cienciano, Melgar y Atlético Grau ya conocen a sus rivales en la Copa Sudamericana 2025. Así quedaron ubicados tras el sorteo de la competencia.
Cienciano, Melgar, and Atlético Grau learned their Copa Sudamericana 2025 group stage opponents following the draw on March 17, 2025. Melgar will face Lanús, Vasco da Gama, and Puerto Cabello. Cienciano will compete against Atlético Mineiro, Caracas, and Deportes Iquique. Atlético Grau is grouped with Gremio, Godoy Cruz, and Sport Luqueño. Cienciano qualified after defeating ADT in a penalty shootout, while Atlético Grau defeated Cusco FC. Melgar entered the Sudamericana after being eliminated from the Copa Libertadores.